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Betamethasone Dipropionate
  • Professionals
  • FDA PI

Betamethasone Dipropionate

Dosage form: cream
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on Dec 1, 2021.

Betamethasone Dipropionate Description

Betamethasone Dipropionate cream USP, 0.05% contains Betamethasone Dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Betamethasone Dipropionate, USP is a white to almost white crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol and freely soluble in acetone, methylene chloride and chloroform.

Chemically, it is 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate. The structural formula is:

Molecular Formula : C28H37FO7

Molecular Weight : 504.60

Each gram contains 0.64 mg Betamethasone Dipropionate, USP (equivalent to 0.5 mg betamethasone) in a white to off-white cream of cetomacrogol 1000, cetostearyl alcohol, mineral oil, purified water, sodium phosphate monobasic, white petrolatum and chlorocresol is present as preservative.

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