Bismuth subcitrate potassium, metronidazole, and tetracycline

Generic name: bismuth subcitrate potassium, metronidazole, and tetracycline [ BIZ-muth-sub-SIT-rate-poe-TASS-ee-um, MET-roe-NYE-da-zole, TET-ra-SYE-kleen ]
Brand name: Pylera
Dosage form: oral capsule (140 mg-125 mg-125 mg)
Drug class:H. pylori eradication agents

Medically reviewed by Drugs.com on Sep 14, 2021. Written by Cerner Multum.

What is bismuth subcitrate potassium, metronidazole, and tetracycline (Pylera)?

Bismuth subcitrate potassium, metronidazole, and tetracycline (Pylera) is a combination medicine used to treat peptic ulcer (duodenal ulcer) with Helicobacter pylori infection. Pylera is usually given together with omeprazole (Prilosec).

Pylera may also be used for purposes not listed in this medication guide.

Warnings

Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking Pylera and for at least 3 days after you stop taking it.

Metronidazole has caused cancer in animal studies. It is not known whether this would occur in humans taking Pylera.

Before taking this medicine

You should not use Pylera if you are allergic to bismuth subcitrate potassium, metronidazole, or tetracycline, or if:

• you have severe kidney disease;

• you drink alcohol daily;

• you regularly consume foods or medicines that contain propylene glycol;

• you took disulfiram (Antabuse) within the past 14 days; or

• you also use methoxyflurane.

Tell your doctor if you have ever had:

• kidney disease;

• liver disease;

• Cockayne syndrome (a rare genetic disorder);

• a blood cell disorder; or

• any type of infection.

Metronidazole has caused cancer in animal studies. It is not known whether this would occur in humans taking Pylera. Ask your doctor about your risk.

Do not use Pylera if you are pregnant. Tetracycline can cause permanent tooth discoloration and affect growth in the baby.

Pylera can make birth control pills less effective. Ask your docto...