Boceprevir (Oral)

Medically reviewed by Drugs.com. Last updated on Mar 23, 2022.

Commonly used brand name(s)

In the U.S.

• Victrelis

Pharmacologic Class: Protease Inhibitor

Uses for boceprevir

Boceprevir is used in combination with injectable peginterferon alfa (Pegasys®, Pegintron®) and ribavirin (Copegus®, Rebetol®) to treat chronic hepatitis C infection. These medicines are used in patients with compensated liver disease (including cirrhosis), who have not been treated before or who have received other medicines but did not work well. Boceprevir is a direct-acting antiviral agent that treats hepatitis C infection.

Boceprevir is available only with your doctor's prescription.

Before using boceprevir

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For boceprevir, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to boceprevir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of boceprevir in the pediatric population. Safety and efficacy have not been established.

Geriatric

Although appropriate studies on the relationship of age to the effects of boceprevir have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have age-related liver problems, which may require caution in patients receiving boceprevir.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking boceprevir, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using boceprevir with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Alfuzosin
• Alprazolam
• Carbamazepine
• Cisapride
• Colchicine
• Conivaptan
• Dihydroergotamine
• Doxazosin
• Doxorubicin
• Doxorubicin Hydrochloride Liposome
• Dronedarone
• Drospirenone
• Eletriptan
• Eliglustat
• Enzalutamide
• Eplerenone
• Ergonovine
• Ergotamine
• Finerenone
• Flibanserin
• Fosphenytoin
• Isavuconazonium Sulfate
• Ivabradine
• Lomitapide
• Lovastatin
• Lurasidone
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