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Bontril
  • Treatments
  • Obesity

Bontril

Generic name:phendimetrazinefen-di-MEH-tra-zeen ]
Brand names: Bontril, Melfiat
Drug classes:Anorexiants, CNS stimulants

Medically reviewed by Melisa Puckey, BPharm. Last updated on Jun 8, 2022.

What is Bontril?

Bontril is similar to an amphetamine. Phendimetrazine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Bontril is used together with diet and exercise to treat obesity.

Bontril may also be used for purposes not listed in this medication guide.

Warnings

You should not use Bontril if you have glaucoma, overactive thyroid, severe heart problems, uncontrolled high blood pressure, advanced coronary artery disease, extreme agitation, or a history of drug abuse.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. A dangerous drug interaction could occur, leading to serious side effects.

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Bontril if you are pregnant.

Do not stop using Bontril suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine. Do not crush, chew, break, or open the extended-release capsule. Swallow the capsule whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

Before taking this medicine

You should not use Bontril if you are allergic to phendimetrazine, or if you have:

  • severe heart problems;

  • advanced coronary artery disease (clogged arteries);

  • severe or uncontrolled high blood pressure;

  • overactive thyroid;

  • glaucoma;

  • extreme agitation or nervousness; or

  • a history of drug abuse.

Do not use Bontril if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, seleg...