Bosentan
Generic name: bosentan [ boe-SEN-tan ]
Brand name: Tracleer
Dosage forms: oral tablet (125 mg; 62.5 mg); oral tablet, dispersible (32 mg)
Drug class:Agents for pulmonary hypertension
What is bosentan?
Bosentan lowers blood pressure in your lungs, helping your heart pump blood more efficiently.
Bosentan is used to treat pulmonary arterial hypertension (PAH) in adults and children who are at least 3 years old. It improves your ability to exercise and prevents your condition from getting worse.
Bosentan is available only under a special program from a certified pharmacy. You must be registered in the program and understand the risks and benefits of taking this medication.
Bosentan may also be used for purposes not listed in this medication guide.
Warnings
Do not use bosentan if you are pregnant or think you might be pregnant. You will need to take a pregnancy test before, during, and after treatment with bosentan. Use highly effective birth control to prevent pregnancy while using bosentan and for at least 30 days after your last dose.
Certain other medicines can interact with bosentan and should not be used at the same time. Tell your doctor about all your current medicines.
Bosentan can cause severe liver problems. Your liver function will need to be tested often.
Call your doctor right away if you have have signs of liver problems such as nausea, vomiting, fever, upper stomach pain, tiredness, or jaundice (yellowing of the skin or eyes).
Bosentan is available only from a certified pharmacy under a special program.
Before taking this medicine
You should not use bosentan if you are allergic to it, or if you are pregnant or might become pregnant during treatment.
Some medicines can cause unwanted or dangerous effects when used with bosentan. Your doctor may change your treatment plan if you also use:
Tell your doctor if you have ever had:
diabetes;
an autoimmune disorder such as rheumatoid arthritis or psoriasis; or
a heart or kidney transplant.
Do not use bosentan if y...
