Acuflex

Generic name:acetaminophen and phenyltoloxamine [ a-seet-a-MIN-oh-fen-and-FEN-il-toe-LOX-a-meen ]
Brand names: Aceta-Gesic, Acuflex, Alpain, Apagesic, BeFlex, ... show all 25 brands BP Poly-650, Dologesic, Flextra-650, Flextra-DS, Genasec, Hyflex-650, Hyflex-DS, Lagesic, Major-gesic, Percogesic, Phenagesic, Phenylgesic, Q Flex, Q-Gesic, Relagesic, RhinoFlex, RhinoFlex 650, Staflex, Vistra, Vitoxapap
Drug class:Analgesic combinations

Medically reviewed by Philip Thornton, DipPharm. Last updated on Feb 17, 2021.

What is Acuflex?

Acuflex contains a combination of acetaminophen and phenyltoloxamine. Acetaminophen is a pain reliever and a fever reducer. Phenyltoloxamine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Acuflex is used to treat runny nose, sneezing, and pain or fever caused by the common cold, flu, or seasonal allergies.

Warnings

Do not use Acuflex if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take Acuflex before the MAO inhibitor has cleared from your body.

Acuflex can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor's advice, and never take more than 2 grams (2000 mg) of acetaminophen per day.

Do not take Acuflex without your doctor's advice if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take acetaminophen.

Before taking this medicine?

You should not take Acuflex if you are allergic to acetaminophen or phenyltoloxamine. Do not use Acuflex if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take this medicine before the MAO inhibitor has cleared from your body.

Before taking Acuflex, tell your doctor if you are allergic to any drugs, or if you have:

• liver or kidney disease;

• diabetes;

• glaucoma;

• urination problems;

• an enlarged prostate;