Bupivacaine and epinephrine (Injection)

Medically reviewed by Drugs.com. Last updated on Jan 21, 2022.

Available Dosage Forms:

• Solution

Therapeutic Class: Anesthetic, Amino Amide Combination

Pharmacologic Class: Sympathomimetic

Chemical Class: Bupivacaine

Uses for bupivacaine and epinephrine

Bupivacaine and epinephrine combination injection is used to numb an area of your body during surgery or other procedures, childbirth, or dental work. It is a local anesthetic.

Bupivacaine and epinephrine is to be given only by or under the direct supervision of your doctor.

Before using bupivacaine and epinephrine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For bupivacaine and epinephrine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to bupivacaine and epinephrine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of bupivacaine and epinephrine combination injection in the pediatric population. Use is not recommended in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bupivacaine and epinephrine combination injection in the elderly. However, elderly patients are more likely to have low blood pressure or kidney problems, which may require caution and an adjustment in the dose for patients receiving bupivacaine and epinephrine.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving bupivacaine and epinephrine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using bupivacaine and epinephrine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Dihydroergotamine
• Isocarboxazid
• Linezolid
• Phenelzine
• Tranylcypromine

Using bupivacaine and epinephrine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amifampridine
• Amineptine
• Amitriptyline
• Amitrip...