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Bupivacaine liposome
  • Treatments
  • Pain

Bupivacaine liposome

Generic name: bupivacaine liposome [ bue-PIV-a-kane-LYE-poe-some ]
Brand name: Exparel
Dosage form: injectable suspension (1.3% (13.3 mg/mL))
Drug class:Local injectable anesthetics

Medically reviewed by Drugs.com on Apr 13, 2022. Written by Cerner Multum.

What is bupivacaine liposome?

Bupivacaine is an anesthetic (numbing medicine) that blocks nerve impulses in your body.

Bupivacaine liposome is used as a local (in only one area) anesthetic to numb an area of your body for a minor surgery such as bunion removal or hemorrhoid surgery.

Bupivacine liposome is also used as a nerve block after surgery on your shoulder or upper arm, to provide pain relief to the area.

Bupivacaine may also be used for purposes not listed in this medication guide.

Warnings

You may still feel numb or be unable to move the numbed area for up to 5 days after you are treated with bupivacaine liposome.

Before taking this medicine

You should not be treated with bupivacaine if you are allergic to it.

Tell your doctor if you have ever had:

  • an allergic reaction to any type of numbing medicine;

  • liver disease;

  • kidney disease;

  • heart disease;

  • a heart rhythm disorder; or

  • seizures.

It is not known whether bupivacaine liposome will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

How is bupivacaine liposome given?

Bupivacaine is given as an injection placed into an area near your surgical incision. You will receive this injection in a hospital or surgical setting.

Bupivacaine liposome can have long-lasting or delayed effects. For at least 4 days (96 hours) after your surgery, tell any doctor or dentist who treats you that you recently received a bupivacaine liposome injection.

Call your doctor if you have joint pain or stiffness, or weakness in any part of your body that occurs after your surgery, even months later.

What happens if I miss a dose?

Since bupivacaine liposome is used as a single dose, it does not have a daily dosing schedule.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving bupivacaine liposome?

For at least 4 days (96 hours) after surgery, avoid using any pain or numbing medicines that contain lidocaine. This includes skin patches, sprays, creams, ointments, or gels applied to th...