Bupropion and naltrexone
Generic name: bupropion and naltrexone [ bue-PRO-pee-on-and-nal-TREX-own ]
Brand name: Contrave
Dosage form: oral tablet, extended release (90 mg-8 mg)
Drug class:Anorexiants
What is bupropion and naltrexone?
Bupropion is an antidepressant medicine that can also decrease appetite. Naltrexone is usually given to block the effects of opioids or alcohol in people with addiction problems. Naltrexone may also curb hunger and food cravings.
Bupropion and naltrexone is a combination medicine used to help manage weight in obese or overweight adults with weight-related medical problems. bupropion and naltrexone is used together with diet and exercise.
Bupropion and naltrexone will not treat any weight-related medical condition, such as high blood pressure, diabetes, or high cholesterol.
Contrave is not approved to treat depression or other psychiatric conditions, or to help you quit smoking.
Bupropion and naltrexone may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you have uncontrolled high blood pressure, seizures, an eating disorder, opioid addiction, if you are pregnant, if you take opioid medicine or other forms of bupropion, or if you have suddenly stopped using alcohol, seizure medication, or a sedative.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with bupropion and naltrexone, and some drugs should not be used together.
Some young people have thoughts about suicide when first taking bupropion. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Before taking this medicine
Do not use bupropion and naltrexone if you are pregnant.Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Tell your doctor right away if you become pregnant.
You should not use this medicine if you are allergic to bupropion or naltrexone, or if you have:
untreated or uncontrolled high blood pressure;
an eating disorder (anorexia or bulimia);
a history of seizures;
opioid addiction or withdrawal (or if you take methadone or buprenorphine);
