C1 esterase inhibitor, human (Intravenous)

Medically reviewed by Drugs.com. Last updated on Jan 25, 2022.

Commonly used brand name(s)

In the U.S.

• Berinert
• Cinryze
• Haegarda

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Immune Modulator

Uses for c1 esterase inhibitor, human

C1 esterase inhibitor is used to treat or prevent hereditary angioedema (HAE). HAE is a rare disease that causes swelling of the face, hands, feet, throat, stomach, bowels, or genitals. People who have HAE have low levels of C1 esterase inhibitor in their body. C1 esterase inhibitor, human helps increase the amount of C1 esterase inhibitors in the body.

C1 esterase inhibitor, human is available only with your doctor's prescription.

Before using c1 esterase inhibitor, human

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For c1 esterase inhibitor, human, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to c1 esterase inhibitor, human or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Berinert® in children.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Cinryze® in children 6 years of age and older. Safety and efficacy have been established.

Appropriate studies have not been performed on the relationship of age to the effects of Haegarda® in children younger than 8 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies have not been performed on the relationship of age to the effects of Berinert® in the geriatric population. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Haegarda® or Cinryze® in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving Cinryze®.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating cer...