Generic name:acalabrutinib [ a-KAL-a-BROO-ti-nib ]
Drug class:BTK inhibitors
What is Calquence?
Calquence blocks the action of certain enzymes in the body, which can interfere with the growth and spread of cancer cells.
Calquence is used to treat mantle cell lymphoma (a type of non-Hodgkin lymphoma) in adults. This medicine is given after other treatments have failed.
Calquence was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, patients responded to this medicine. However, further studies are needed.
Calquence is also used to treat chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) in adults.
Warnings
Calquence can make it easier for you to bleed. Contact your doctor or seek emergency medical attention if you have any bleeding that will not stop.
Call your doctor at once if you have signs of bleeding inside your body, such as: dizziness, weakness, confusion, headache, speech problems, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds.
Before taking this medicine
You should not use Calquence if you are allergic to acalabrutinib.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
an active or chronic infection;
a heart rhythm disorder;
bleeding problems; or
hepatitis B (acalabrutinib can cause this condition to come back or get worse).
Taking Calquence may increase your risk of developing other types of cancer, such as skin cancer. Talk to your doctor about this risk and what skin symptoms to watch for.
It is not known whether acalabrutinib will harm an unborn baby. Tell y...
