Camzyos

Generic name: mavacamten
Dosage form: capsules

Medically reviewed by Judith Stewart, BPharm. Last updated on May 11, 2022.

What is Camzyos?

Camzyos is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM).

Camzyos may improve your symptoms and your ability to be active.

Important information

Camzyos may cause serious side effects, including:

• Heart failure, a condition where the heart cannot pump with enough force. Heart failure is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with
  Camzyos to help your healthcare provider understand how your heart is responding to Camzyos. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment.
  Tell your healthcare provider or get medical help right away if you develop new or worsening:
  
  • shortness of breath
  • chest pain
  • fatigue
  • swelling in your legs
  • a racing sensation in your heart (palpitations)
  • rapid weight gain
• The risk of heart failure is also increased when Camzyos is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment.
• Because of the serious risk of heart failure, Camzyos is only available through a restricted program called the Camzyos Risk Evaluation and Mitigation Strategy (REMS) Program.
  • Your healthcare provider must be enrolled in the Camzyos REMS Program in order for you to be prescribed Camzyos.
  • Before you start treatment, you must enroll in the Camzyos REMS Program. Talk to your healthcare provider about how to enroll in the Camzyos REMS Program. You will be given information about the program when you enroll.
  • Before you start treatment, your healthcare provider and pharmacist will make sure you understand how to take Camzyos safely, which will include returning for echocardiograms when advised by your healthcare provider.
    Camzyos can only be dispensed by a certified pharmacy that participates in the Camzyos REMS Program.
    Your healthcare provider can give you information on how to find a certified pharmacy. You will not be able to get Camzyos at a local pharmacy.
  • If you have questions about the Camzyos REMS Program, ask your healthcare provider, go to www.CamzyosREMS.com, or call 1-833-628-7367.

See Camzyos side effects for information about side effects.

Before you take Camzyos

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

• are pregnant or plan to become pregnant. Camzyos may harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment. You may also report your pregnancy by calling Bristol-Myers Squibb at 1-800-721-5072 or www.bms.com.
  If you are a female and able to become pregnant:
  • Your healthcare provider will do a pregnancy test before you start treatment.