Cangrelor (Intravenous)

Medically reviewed by Drugs.com. Last updated on Mar 25, 2022.

Commonly used brand name(s)

In the U.S.

• Kengreal

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Platelet Aggregation Inhibitor

Pharmacologic Class: ADP-Induced Aggregation Inhibitor

Uses for cangrelor

Cangrelor injection is used in patients undergoing percutaneous coronary intervention (PCI) to lower the risk of blood clots and heart attack.

A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Cangrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of cangrelor may also increase the chance of serious bleeding in some people.

Cangrelor is to be given only by or under the supervision of your doctor.

Before using cangrelor

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cangrelor, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to cangrelor or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of cangrelor injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cangrelor injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving cangrelor, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using cangrelor with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Abrocitinib

Using cangrelor with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aceclofenac
• Acemetacin
• Amtolmetin Guacil
• Apixaban
• Argatroban
• Betrixaban
• Bivalirudin
• Bromfenac
• Bufexamac
• Caplacizumab-yhdp
• Celecoxib
• Choline Salicylate
• Citalopram
• Clonixin...