Capmatinib
Generic name: capmatinib [ kap-MA-ti-nib ]
Brand name: Tabrecta
Dosage form: oral tablet (150 mg; 200 mg)
Drug class:Multikinase inhibitors
What is capmatinib?
Capmatinib is used to treat non-small cell lung cancer that has spread to other parts of the body (metastatic) or cannot be removed with surgery.
Capmatinib is used only if your cancer has a specific genetic marker (an abnormal "MET" gene). Your doctor will test you for this gene.
Capmatinib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to capmatinib, but further studies are needed.
Capmatinib may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Tell your doctor if you have ever had:
lung problems other than lung cancer; or
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using capmatinib should use effective birth control to prevent pregnancy. Capmatinib can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using capmatinib.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
How should I take capmatinib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take capmatinib with or without food.
You will need frequent blood tests to check your liver function.
Do not change your dose or stop taking this medicine without your doctor's advice.
Swallow the tablet whole and do not crush, chew, or break it.
If you vomit shortly after taking capmatinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
Throw away any tablets that are left 6 weeks after you first opened the bottle.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses a...
