Capreomycin (Injection)
Medically reviewed by Drugs.com. Last updated on May 14, 2022.
The use of capreomycin in patients with renal insufficiency or preexisting auditory impairment must be undertaken with great caution, and the risk of additional cranial nerve VIII impairment or renal injury should be weighed against the benefits to be derived from therapy. Since other parenteral antituberculosis agents (streptomycin, viomycin) also have similar and sometimes irreversible toxic effects, particularly on cranial nerve VIII and renal function, simultaneous administration of these agents with capreomycin is not recommended. Use with nonantituberculosis drugs (polymyxin A sulfate, colistin sulfate, amikacin, gentamicin, tobramycin, vancomycin, kanamycin, and neomycin) having ototoxic or nephrotoxic potential should be undertaken only with great caution. The safety of the use of capreomycin in pregnancy has not been determined. Safety and effectiveness in pediatric patients have not been established .
Commonly used brand name(s)
In the U.S.
- Capastat Sulfate
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antitubercular
Chemical Class: Aminoglycoside
Uses for capreomycin
Capreomycin injection is used together with other medicines to treat tuberculosis (TB) in patients who have received other medicines that did not work well. Capreomycin is an aminoglycoside antibiotic that works by killing bacteria or preventing their growth.
Capreomycin is to be given only by or under the direct supervision of your doctor.
Before using capreomycin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For capreomycin, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to capreomycin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of capreomycin injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of capreomycin injection in the elderly. However, elderly patients are more likely to have kidney and hearing problems, which may require caution and an adjustment in the dose for patients receiving capreomycin.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving capreomycin, it is especially important that your healthcar..
