Medically reviewed by Drugs.com. Last updated on Apr 22, 2022.
Serious InfectionsIncreased risk of serious infections leading to hospitalization or death, including tuberculosis (TB), bacterial sepsis, invasive fungal infections (such as histoplasmosis), and infections due to other opportunistic pathogens.Discontinue adalimumab-adaz if a patient develops a serious infection or sepsis during treatment.Perform test for latent TB; if positive, start treatment for TB prior to starting adalimumab-adaz.Monitor all patients for active TB during treatment, even if initial latent TB test is negative.MalignancyLymphoma and other malignancies, some fatal, have been reported in children and adolescent patients treated with TNF-blockers including adalimumab products.Post-marketing cases of hepatosplenic T-cell lymphoma (HSTCL), a rare type of T-cell lymphoma, have occurred in adolescent and young adults with inflammatory bowel disease treated with TNF-blockers including adalimumab products .
Commonly used brand name(s)
In the U.S.
- Hyrimoz
Pharmacologic Class: Adalimumab
Uses for adalimumab-adaz
Adalimumab-adaz injection is used to treat the symptoms and prevent the progression of moderate to severely active rheumatoid arthritis and active ankylosing spondylitis. It is used in children 4 years of age and older for juvenile idiopathic arthritis. Adalimumab-adaz is also used to treat psoriatic arthritis, which is a type of arthritis that causes pain and swelling in the joints along with patches of scaly skin on some areas of the body. Psoriatic arthritis usually occurs with a skin condition called psoriasis. Adalimumab-adaz may be used alone or in combination with other medicines (eg, methotrexate).
Adalimumab-adaz injection is also used to treat the symptoms of active Crohn's disease in adult patients who have not been helped by other medicines, including infliximab. It is also used to treat moderate to severe ulcerative colitis in patients who have been treated with other medicines (eg, azathioprine, corticosteroids, or 6-mercaptopurine) that did not work well.
Adalimumab-adaz injection is also used to treat moderate to severe chronic plaque psoriasis, which is a skin diseas..
