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Cedazuridine and decitabine
  • Treatments
  • Myelodysplastic Syndrome

Cedazuridine and decitabine

Generic name: cedazuridine and decitabine [ SED-az-URE-i-deen-and-de-SIT-a-been ]
Brand name: Inqovi
Dosage form: oral tablet (100 mg-35 mg)
Drug class:Antineoplastic combinations

Medically reviewed by Drugs.com on Oct 16, 2020. Written by Cerner Multum.

What is cedazuridine and decitabine?

Cedazuridine and decitabine is a combination medicine that is used to treat myelodysplastic syndromes (certain types of blood or bone marrow disorders).

Cedazuridine and decitabine may also be used for purposes not listed in this medication guide.

Warnings

Cedazuridine and decitabine affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, cough, mouth sores, or unusual bleeding or bruising.

Before taking this medicine

Tell your doctor if you have ever had:

You may need to have a negative pregnancy test before starting this treatment.

Cedazuridine and decitabine can harm an unborn baby or cause birth defects if the mother or the father is using cedazuridine and decitabine.

  • If you are a woman, do not use cedazuridine and decitabine if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.

  • If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.

  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is using this medicine.

Cedazuridine and decitabine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because the medicine can harm an unborn baby.

You should not breastfeed while using cedazuridine and decitabine and for at least 2 weeks after your last dose.

Cedazuridine and decitabine is not approved for use by anyone younger than 18 years old.

How should I take cedazuridine and decitabine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Cedazuridine and decitabine is given in a 28-day treatment cycle. You may need to use the medicine only during the first 5 days of each cycle. Your doctor will determine how long to treat you with this medicine.

Take cedazuridine and decitabine on an empty stomach, at least 2 hours before or 2 hours after a meal.

Take the medicine at the same time each day.

Swallow the tablet whole and do not crush, chew, or break it....