Class: First Generation Cephalosporins
CAS Number: 27164-46-1
Brands: Ancef
Introduction
Antibacterial; β-lactam antibiotic; first generation cephalosporin.
Uses for ceFAZolin
Biliary Tract Infections
Treatment of biliary tract infections caused by susceptible Escherichia coli, Klebsiella, Proteus mirabilis, Staphylococcus aureus, or various streptococci.
Bone and Joint Infections
Treatment of bone and joint infections caused by susceptible S. aureus.
Endocarditis
Treatment of endocarditis caused by susceptible Streptococcus pyogenes. AHA recommends cefazolin as an alternative for treatment of staphylococcal endocarditis or endocarditis caused by viridans streptococci†, S. bovis†, S. pneumoniae†, S. pyogenes, or groups B, C, and G streptococci† in penicillin-allergic individuals; should not be used in those with immediate-type penicillin hypersensitivity (see Cross-hypersensitivity under Cautions).
Alternative for prevention of α-hemolytic (viridans group) streptococcal endocarditis† in individuals undergoing certain dental or upper respiratory tract procedures who have cardiac conditions that put them at highest risk. Oral amoxicillin is usual drug of choice for such prophylaxis; cefazolin (or ceftriaxone) is an alternative in penicillin-allergic individuals or when an oral anti-infective cannot be used. Should not be used in those with immediate-type penicillin hypersensitivity (see Cross-hypersensitivity under Cautions). Consult most recent AHA recommendations for specific information on which cardiac conditions are associated with highest risk of endocarditis and which procedures require prophylaxis.
Respiratory Tract Infections
Treatment of respiratory infections caused by susceptible S. pneumoniae, S. pyogenes (...
