Cefiderocol (Intravenous)

Medically reviewed by Drugs.com. Last updated on Mar 28, 2022.

Commonly used brand name(s)

In the U.S.

Fetroja

Available Dosage Forms:

Powder for Solution

Therapeutic Class: Antibiotic

Pharmacologic Class: Cephalosporin

Uses for cefiderocol

Cefiderocol injection is used to treat complicated urinary tract infection (including pyelonephritis) in patients who have limited or no other treatment options. It is also used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP). Cefiderocol is an antibiotic. It works by killing bacteria or preventing their growth. However, cefiderocol will not work for colds, flu, or other virus infections.

Cefiderocol is to be given only by or under the direct supervision of your doctor.

Before using cefiderocol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cefiderocol, the following should be considered:

Allergies

The dose of cefiderocol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of cefiderocol. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of cefiderocol injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefiderocol injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefiderocol injection.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Cefiderocol Intravenous