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Cenobamate
  • Treatments
  • Seizures

Cenobamate

Generic name: cenobamate [ SEN-oh-BAM-ate ]
Brand names: Xcopri, Xcopri Titration Pack, Xcopri Maintenance Pack
Dosage form: oral tablet (100 mg; 12.5 mg-25 mg; 150 mg; 150 mg-200 mg; 200 mg; 250 mg daily-dose; 350 mg daily-dose; 50 mg; 50 mg-100 mg)
Drug class:Carbamate anticonvulsants

Medically reviewed by Drugs.com on May 17, 2022. Written by Cerner Multum.

What is cenobamate?

Cenobamate is used to treat partial-onset seizures in adults.

Cenobamate may also be used for purposes not listed in this medication guide.

Warnings

Cenobamate can cause serious or life-threatening allergic reactions that can affect your liver, blood cells, or other parts of the body. Call your doctor or get emergency medical help if you have symptoms such as: severe weakness or muscle pain, a fever, swollen glands, unusual bruising or bleeding, swelling in your face or throat, trouble breathing, hives or a rash, yellowing of your skin or eyes, or any illness that does not get better.

Some people have thoughts about suicide while taking cenobamate. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Do not stop using cenobamate suddenly. Follow your doctor's instructions about tapering your dose.

Before taking this medicine

You should not use cenobamate if you are allergic to it, or if you have:

  • a genetic heart rhythm disorder called short QT syndrome.

Tell your doctor if you have ever had:

  • depression, or a mood disorder;

  • suicidal thoughts or actions;

  • liver or kidney disease;

  • a blood cell disorder; or

  • an allergic reaction to a medicine that caused a rash or affected your internal organs or blood cells.

Some people have thoughts about suicide while taking cenobamate. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Do not start or stop taking seizure medication during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.

Cenobamate can make birth control pills less effective. Ask your doctor about using a non-oral birth control to prevent pregnancy. This includes injections, implants, skin patches, vaginal rings, condom, diaphragm, cervical cap, or contraceptive sponge.

If you are pregna...