Cerisa Wash

Generic name:sulfacetamide sodium and sulfur
Dosage form: lotion
Drug class:Topical antibiotics

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

(Sodium Sulfacetamide 10% and Sulfur 1%)

Rx only

Cerisa Wash Description

Each gram of CERISA™ WASH contains 100mg of Sodium Sulfacetamide and 10mg of Sulfur in a wash containing Butylated Hydroxytolulene, Cetyl Alcohol, Disodium EDTA, Glyceryl Stearate and PEG-l00 Stearate, Lactic Acid, Magnesium Aluminum Silicate, Methyl Paraben, Propyl Paraben, Purified Water, Sodium C14-16 Olefin Sulfonate, Sodium Hydroxide, Sodium Thiosulfate, Stearyl alcohol, White Petrolatum and Xanthan Gum.

Sodium Sulfacetamide is a sulfonamide with antibacterial activity while sulfur acts as a keratolytic agent. Chemically, Sodium Sulfacetamide is N-{(4-aminophenyl) sulfony}-acetamide, monosodium salt, monohydrate.

The structural formula is:

Cerisa Wash - Clinical Pharmacology

The most widely accepted mechanism of action of sulfonamides in the Woods-Fildes theory which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid (PABA), an essential component for bacterial growth. While absorption through intact skin has not been determined, Sodium Sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine, largely unchanged. The biological half-life has variously been reported as 7 to 12.8 hours.

The exact mode of action of sulfur in the treatment of acne is unknown, but it has been reported that it inhibits the growth of Propionibacterium acnes and the formation of free fatty acids.

Indications and Usage for Cerisa Wash

CERISA™ WASH is indicated in the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis.

Contraindications

CERISA™ WASH is contraindicated for use by patients having known hypersensitivity to sulfonamides, sulfur or any other component of this preparation. CERISA™ W...