Generic name: chloramphenicol
Dosage form: Otic Solution
Drug class:Otic anti-infectives
Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.
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WARNING
Bone marrow hypoplasia including aplastic anemia and death has been reported following local application of chloramphenicol. Chloramphenicol should not be used when less potentially dangerous agents would be expected to provide effective treatment.
Description
Each milliliter of Chloromycetin Otic contains 5 mg (0.5%) chloramphenicol in propylene glycol. Sterile.
The chemical names for chloramphenicol are:
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl) ethyl]-, and
D-threo-(—)-2,2-Dichloro-N-[β,-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl] acetamide.
Chloramphenicol has the following empirical and structural formulas:
Clinical Pharmacology
Chloramphenicol is a broad-spectrum antibiotic originally isolated from Streptomyces venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis by interfering w...
