Chlorphen Mal, Dex HBr, Pseudoeph

Generic name: chlorpheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide
Dosage form: solution/ drops
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Chlorphen Mal, Dex HBr, Pseudoeph Description

Chlorphen Mal/Dex HBr/Pseudoeph HCl 0.8/3/9 mg Drops is an antihistaminic, antitussive, and decongestant drop for oral administration.

Each dropperful (1 mL) contains:
Chlorpheniramine Maleate, USP ..... 0.8 mg
Dextromethorphan HBr, USP ..... 3 mg
Pseudoephedrine HCl, USP ..... 9 mg

Inactive Ingredients
Glycerin, Propylene Glycol, Sorbitol, Citric Acid, Sodium Citrate, Sodium Saccharin, Grape Flavor, FDC Blue #1, FDC Red #40, Purified Water.

Chlorpheniramine maleate is an antihistamine having the chemical name, 2-[p-Chloro- -[2-(dimethylamino)ethyl]benzyl]pyridine maleate(1:1), with the following structure:


Dextromethorphan hydrobromide is an antitussive having the chemical name, (Morphinan,3-methoxy-17-methyl-,(9,13 ,14 )-,hydrobromide, monohydrate), with the following structure:


Pseudoephedrine hydrochloride is a decongestant having the chemical name, (Benzenemethanol,-[1-(methylamino)ethyl]-, [S-(R*,R*)]-,hydrochloride) with the following structure:

Chlorphen Mal, Dex HBr, Pseudoeph - Clinical Pharmacology

Antihistaminic, antitussive, and decongestant actions.

Chlorpheniramine Maleate
Chlorpheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines.

Antihistamines compete with histamine for receptor sites on effector cells. Chlorpheniramine also ha