Chlorpheniramine and phenylephrine

Generic name: chlorpheniramine and phenylephrine [ KLOR-fen-IR-a-meen-and-FEN-il-EFF-rin ]
Brand names: Actifed Cold & Allergy, Allan Tannate Pediatric, Allerest PE, BP Allergy JR, ChlorTan D, ... show all 66 brands Cold & Allergy Relief, Dallergy Drops, Ed A-Hist, Ed ChlorPed D, NoHist LQ, Phenagil, R-Tanna, Sinus & Allergy PE, Sudafed PE Sinus & Allergy, Phenylhistine, Novahistine Elixir, Histatab Plus, Ed A-Hist LA, Rynatan Pediatric, Rynatan, Phenchlor Tannate Pediatric, Relera, Rondec Drops, Rondec, Ceron, Ceron Drops, Chlor-Mes Jr, Dallergy-JR, Rondex, Rondex Drops, Ny-Tannic, Dec-Chlorphen, Dec-Chlorphen Drops, C Phen Drops, C Phen, Tannate Pediatric, Histadec, PediaTan D, Sudafed PE Sinus and Allergy, Rescon-Jr, CP Dec, Cardec Drops, P-Tann D, Triaminic Cold/Allergy, Rinate Pediatric, Cardec, AlleRx, Sildec-PE Drops, Sildec-PE, Nasohist Pediatric, Sinus and Allergy PE, PD-Hist D Drops, PD-Hist D, CP Dec Drops, Tanahist-D, Ry-Tann, Sonahist, Cold and Allergy Relief, Sinus and Allergy Maximum Strength, Actifed Cold and Allergy, NoHist, Trigofen Drops, Lohist, Virdec, Maxichlor PEH, Giltuss Allergy and Sinus
Dosage forms: oral liquid (1 mg-2.5 mg/5 mL; 1 mg-2.5 mg/mL; 2 mg-5 mg/mL; 4 mg-10 mg/5 mL); oral suspension (4.5 mg-5 mg/5 mL); oral suspension, extended release (4 mg-20 mg/5 mL; 8 mg-10 mg/5 mL); oral tablet (3.5 mg-10 mg; 4 mg-10 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Mar 10, 2022. Written by Cerner Multum.

What is chlorpheniramine and phenylephrine?

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine and phenylephrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.

Chlorpheniramine and phenylephrine may also be used for purposes not listed in this medication guide.

Warnings

Do not use chlorpheniramine and phenylephrine if you have used an