Chlorpheniramine, dextromethorphan, and phenylephrine

Generic name: chlorpheniramine, dextromethorphan, and phenylephrine [ klor-feh-NEER-a-meen, dex-troe-meh-THOR-fan, and-feh-nill-EH-frin ]
Brand names: Alka-Seltzer Plus Cold and Cough, Balamine DM, Ed A-Hist DM, Gencontuss, Giltuss Allergy Plus, ... show all 73 brands NoHist DM, Robitussin Cough & Allergy, Cerose DM, Tussar DM, Liquituss R-DM, Atuss DM, Norel DM, Poly-Tussin DM, De-Chlor DM, De-Chlor DR, Coldtuss-DR, Tri-Vent DPC, Atuss DR, Corfen-DM, Uni-Tuss DM, Mintuss DR, Trital DM, P Chlor DM, Dex PC, Rondec-DM Drops, Rondec-DM, Donatussin DM Drops, Ceron-DM Drops, Ceron-DM, Rondex-DM, Rondex-DM Drops, Dec-Chlorphen DM, Dec-Chlorphen DM Drops, HistadecDM, CP Dec DM, Neo DM Drops, Cardec DM Drops, Reme Tussin DM, Maxiphen ADT, Tussplex DM, Robitussin Pediatric Cough and Cold Nighttime, Robitussin Cough and Allergy, Robitussin Cough and Cold Nighttime, Cardec DM, C-Phen DM, C-Phen DM Drops, Sildec-PE DM Drops, Sildec-PE DM, Nasohist-DM, DM-PE-Chlor, CP Dec-DM Drops, PD-Cof Drops, PD-Cof, Zotex-12D, Quartuss DM, Nohist-DMX, Sonahist-DM, Relahist-DM, Z-Dex 12 D, Bronkids, Statuss DM, Albatussin SR, NoHist-PDX, Re DCP, Centergy DM, Zoden DM Drops, Trigofen DM Drops, Nasohist-DM Pediatric, Tri-Dex PE, Virdec DM, Norel CS, EndaCof Drops, Giltuss Children's Allergy Plus
Dosage forms: oral liquid (2 mg-10 mg-5 mg/5 mL; 4 mg-15 mg-10 mg/5 mL; 4 mg-20 mg-10 mg/10 mL); oral tablet, effervescent (2 mg-10 mg-5 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Apr 7, 2022. Written by Cerner Multum.

What is chlorpheniramine, dextromethorphan, and phenylephrine?

Chlorpheniramine is an antihistamine. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant.

Chlorpheniramine, dextromethorphan, and phenylephrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

chlorpheniramine, dextromethorphan, and phenylephrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for purposes not listed in this medication guide.