Chlorpheniramine, ibuprofen, and phenylephrine (Oral)

Medically reviewed by Drugs.com. Last updated on Jun 6, 2022.

Available Dosage Forms:

• Tablet

Therapeutic Class: Analgesic/Decongestant Combination

Pharmacologic Class: Chlorpheniramine

Chemical Class: Chlorpheniramine

Uses for chlorpheniramine, ibuprofen, and phenylephrine

Chlorpheniramine, ibuprofen, and phenylephrine combination is used to relieve symptoms of allergies and cold, including fever, headache, itching of the nose and throat, itchy, watery eyes, minor aches and pains, sneezing, or runny or stuffy nose. It also helps reduce swelling of the nasal passages and restores easier breathing through the nose.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used in this combination to relieve inflammation, swelling, and pain.

Chlorpheniramine, ibuprofen, and phenylephrine is available as an over-the-counter (OTC) product.

Before using chlorpheniramine, ibuprofen, and phenylephrine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For chlorpheniramine, ibuprofen, and phenylephrine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to chlorpheniramine, ibuprofen, and phenylephrine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of chlorpheniramine, ibuprofen, and phenylephrine combination in children 12 years of age and older. Chlorpheniramine, ibuprofen, and phenylephrine should not be used in children younger than 12 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of chlorpheniramine, ibuprofen, and phenylephrine combination in the elderly. However, elderly patients more likely to develop age-related stomach problems, which may require caution and an adjustment in the dose for patients receiving chlorpheniramine, ibuprofen, and phenylephrine.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking chlorpheniramine, ibuprofen, and phenylephrine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using chlorpheniramine, ibuprofen, and phenylephrine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or cha...