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Chlorpheniramine, phenylephrine, and phenyltoloxamine
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Chlorpheniramine, phenylephrine, and phenyltoloxamine

Generic name: chlorpheniramine, phenylephrine, and phenyltoloxamine [ KLOR-fen-IR-a-meen, FEN-il-EFF-rin, and-FEEN-il-toe-LOX-a-meen ]
Brand names: Chlorex A, Nalex-A, NoHist-A, West-Decon M, Comhist, ... show all 13 brands
Dosage forms: oral liquid (2.5 mg-5 mg-7.5 mg/5 mL); oral tablet, extended release (4 mg-20 mg-40 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Aug 27, 2021. Written by Cerner Multum.

What is chlorpheniramine, phenylephrine, and phenyltoloxamine?

Chlorpheniramine and phenyltoloxamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, phenylephrine, and phenyltoloxamine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

chlorpheniramine, phenylephrine, and phenyltoloxamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, phenylephrine, and phenyltoloxamine may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline,