Chromic Chloride Injection

Dosage form: injection, solution
Drug class:Minerals and electrolytes

Medically reviewed by Drugs.com. Last updated on Aug 23, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Rx Only

STERILE, NONPYROGENIC, TRACE ELEMENT

ADDITIVE FOR IV USE AFTER DILUTION

(Chromium 4 mcg/mL)

PRESERVATIVE FREE

Chromic Chloride Injection Description

Chromic Chloride Injection, USP is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN). Each mL contains Chromic Chloride Hexahydrate 20.5 mcg, Water for Injection q.s. pH adjusted with Hydrochloric Acid if necessary. It delivers elemental Chromium 4 mcg/mL. The 10 mL vial is a single dose preservative free vial. Discard any unused portion.

Chromic Chloride Injection - Clinical Pharmacology

Trivalent chromium is part of glucose tolerance factor, an activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function.

Providing chromium during TPN prevents development of the following deficiency symptoms: impaired glucose tolerance, ataxia, peripheral neuropathy and a confusional state similar to mild/moderate hepatic encephalopathy.

Indications and Usage for Chromic Chloride Injection

Chromic Chloride Injection, USP is indicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

Contraindications

Chromic Chloride Injection, USP should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis and increased renal loss of chromium from a bolus injection.

Warnings

This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are...