CidalEaze Cream

Generic name:lidocaine hydrochloride
Dosage form: cream
Drug class:Topical anesthetics

Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Rx Only

DESCRIPTION:

CidalEaze (Lidocaine 3% Cream) is a topical anesthetic indicated for the relief of pruritus, pruritic eczemas, abrasions, minor burns, insect bites, pain, soreness, and discomfort due to pruritus ani, pruritus vulvae, hemorrhoids, anal fissures, and similar conditions of the skin and mucous membranes.

ACTIVE INGREDIENTS: Each gram of CidalEaze (Lidocaine 3% Cream) contains lidocaine hydrochloride 3% (30 mg).

INACTIVE INGREDIENTS: aluminum sulfate, calcium acetate, cetyl alcohol, glycerine, glyceryl monostearate SE, methyl paraben, mineral oil, propyl paraben, purified water, sodium hydroxide, sorbitan stearate, stearic acid, stearyl alcohol, and white petrolatum.

CLINICAL PHARMACOLOGY:

MECHANISM OF ACTION:

CidalEaze (Lidocaine 3% Cream) releases lidocaine from a mild acidic vehicle to stabilize the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action. A mild acidic vehicle lowers pH to increase protection against alkaline irritations and to provide a favorable environment for healing.

Lidocaine is chemically designated as acetamide, 2- (diethylamino)-N-(2,6-dimethylphenyl), and has the following structure.

PHARMACOKINETICS:

Lidocaine may be absorbed following topical administration to mucous membranes, its rate and extent of absorption depending upon the specific site of application, duration of exposure, concentration and total dosage. In general, the rate of absorption of local anesthetic agents followi...