Dosage form: tablet, film coated
Drug class:H2 antagonists
Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.
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Cimetidine Tablets Description
Cimetidine is a histamine H2-receptor antagonist. Chemically it is N”-cyano-N-methyl-N’-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]-ethyl], guanidine.
The molecular formula for cimetidine is C10H16N6S; and the molecular weight is 252.35. The structural formula for cimetidine is:

Cimetidine contains an imidazole ring, and is chemically related to histamine. Cimetidine has a bitter taste and characteristic odor.
Solubility Characteristics
Cimetidine is soluble in alcohol, slightly soluble in water, very slightly soluble in chloroform and insoluble in ether.
Each tablet, for oral administration, contains 300 mg, 400 mg, or 800 mg cimetidine, USP. In addition, each tablet contains the following inactive ingredients: corn starch, magnesium stearate, microcrystalline cellulose, povidone, sodium lauryl sulfate and sodi...