Generic name: clindamycin phosphate
Dosage form: gel
Drug classes:Topical acne agents, Vaginal anti-infectives
Medically reviewed by Drugs.com. Last updated on Aug 1, 2021.
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Clindamycin Gel Description
Clindamycin phosphate gel USP, 1%, a topical antibiotic, contains clindamycin phosphate, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 981, methylparaben, polyethylene glycol 400, propylene glycol, purified water, and sodium hydroxide. Chemically, clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7 (S)-chlorosubstitution of the 7 (R)-hydroxyl group of the parent antibiotic, lincomycin, and has the structural formula represented below:
The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-a-D-galacto-octopyranoside 2-(dihydrogen phosphate).
Clindamycin Gel - Clinical Pharmacology
Pharmacokinetics: In an open-label, parallel group study of 24 patients with ...
