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Clindamycin Lotion
  • Professionals
  • FDA PI

Clindamycin Lotion

Generic name: clindamycin phosphate
Dosage form: lotion
Drug classes:Topical acne agents, Vaginal anti-infectives

Medically reviewed by Drugs.com. Last updated on Jan 1, 2022.

For External Use

Clindamycin Lotion Description

Clindamycin Phosphate Topical Lotion, 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter.

Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

The lotion contains cetostearyl alcohol (2.5%); glycerin; glyceryl stearate SE (with potassium monostearate);isostearyl alcohol (2.5%); methylparaben (0.3%); purified water; sodium lauroyl sarcosinate and stearic acid.

The structural formula is represented below:

The chemical name for clindamycin phosphate is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl- trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L- threo-α-D- galacto-octopyranoside 2-(dihydrogen phosphate).

Clindamycin Lotion - Clinical Pharmacology

Mechanism of Action

The mech...