Clobetasol Gel

Generic name: clobetasol propionate
Dosage form: gel
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on Feb 21, 2022.

Rx Only

FOR DERMATOLOGIC USE ONLY.

NOT FOR OPHTHALMIC, ORAL OR INTRAVAGINAL USE.

Clobetasol Gel Description

Clobetasol propionate gel contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Clobetasol propionate is a white to cream-colored crystalline powder insoluble in water. Chemically, it is 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate, and it has the following structural formula:

Each gram of the 0.05% gel contains 0.5 mg clobetasol propionate in a base of propylene glycol, carbomer 934P, sodium hydroxide and purified water.

Clobetasol Gel - Clinical Pharmacology

Like other topical corticosteroids, clobetasol propionat...