Colestipol Suspension

Generic name: colestipol hydrochloride
Dosage form: granule, for oral suspension
Drug class:Bile acid sequestrants

Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.

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Colestipol Suspension Description

Colestipol hydrochloride for oral suspension, USP contains colestipol hydrochloride, which is a lipid lowering agent for oral use. Colestipol hydrochloride is an insoluble, high molecular weight basic anion-exchange copolymer of diethylenetriamine and 1-chloro-2, 3-epoxypropane, with approximately 1 out of 5 amine nitrogens protonated (chloride form). It is a light yellow water-insoluble resin which is hygroscopic and swells when suspended in water or aqueous fluids.

Colestipol hydrochloride for oral suspension, USP is tasteless and odorless. The inactive ingredient is silicon dioxide. One dose (1 packet or 1 level scoopful) of colestipol hydrochloride for oral suspension, USP contains 5 grams of colestipol hydrochloride.

Colestipol Suspension - Clinical Pharmacology

Cholesterol is the major, and probably the sole precursor of bile acids. During normal digestion, bile acids are secreted via the bile from the liver and gall bladder in...