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Colistin, hydrocortisone, neomycin, and thonzonium otic
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Colistin, hydrocortisone, neomycin, and thonzonium (otic)

Generic name: colistin, hydrocortisone, neomycin, and thonzonium (otic) [ koe-LIS-tin, HYE-droe-KOR-ti-sone, NEE-oh-MYE-sin, thon-ZOE-nee-um ]
Brand names: Coly-Mycin S, Cortisporin-TC, Coly Mycin S
Dosage form: otic suspension (0.3%-1%-0.33%-0.05%)
Drug class:Otic steroids with anti-infectives

Medically reviewed by Drugs.com on Sep 14, 2021. Written by Cerner Multum.

What is colistin, hydrocortisone, neomycin, and thonzonium?

Colistin and neomycin are antibiotics that fight bacteria.

Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation.

Thonzonium is a wetting agent.

Colistin, hydrocortisone, neomycin, and thonzonium otic (for the ears) is a combination medicine used to treat outer ear infections caused by bacteria.

colistin, hydrocortisone, neomycin, and thonzonium will not treat a viral infection such as herpes or shingles.

Colistin, hydrocortisone, neomycin, and thonzonium otic may also be used for purposes not listed in this medication guide.

Warnings

You should not use colistin, hydrocortisone, neomycin, and thonzonium if you have a hole in your ear drum (ruptured ear drum).

Before taking this medicine

You should not use this medicine if you are allergic to colistin, hydrocortisone, neomycin, or thonzonium, or if you have a hole in your ear drum (ruptured ear drum).

FDA pregnancy category C. It is not known whether colistin, hydrocortisone, neomycin, and thonzonium otic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Colistin, hydrocortisone, neomycin, and thonzonium otic can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

This medicine should not be used on a child younger than 1 year old.

How should I use colistin, hydrocortisone, neomycin, and thonzonium?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Before using the medicine, clean and dry your ear canal with sterile cotton.

Shake the ear drops well just before each use.

To use the ear drops:

  • Lie down or tilt your head with your ear facing upward. Open the ear canal by gently pulling your ear back, or pulling downward on the earlobe when giving this medicine to a child.

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