Combigan

Generic name:brimonidine and timolol ophthalmic [ bri-MOE-ni-deen-and-TIM-oh-lol-off-THAL-mik ]
Drug class:Ophthalmic glaucoma agents

Medically reviewed by Sophia Entringer, PharmD. Last updated on Jun 10, 2022.

What is Combigan?

Combigan contains a combination of brimonidine and timolol.

Timolol is a beta-blocker that also reduces pressure inside the eye.

Combigan eye drops are used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Combigan may also be used for purposes not listed in this medication guide.

Warnings

You should not use Combigan eye drops if you have a history of asthma or chronic obstructive pulmonary disease (COPD), or a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.

Combigan should not be given to a child younger than 2 years old.

Before taking this medicine

You should not use Combigan eye drops if you are allergic to brimonidine or timolol, or if you have:

• a history of asthma or chronic obstructive pulmonary disease (COPD); or

• a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.

To make sure Combigan is safe for you, tell your doctor if you have:

• congestive heart failure, coronary artery disease, history of stroke or blood clot;

• high or low blood pressure, circulation problems (such as Raynaud's syndrome);

• depression;

• diabetes (using brimonidine and timolol ophthalmic may make it harder for you to tell when you have low blood sugar);

• a thyroid disorder;

• any allergies;

• myasthenia gravis; or

• a history of glaucoma or increased p.