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Comfortis
  • Professionals
  • FDA PI

Comfortis

Generic name: spinosad tablets
Dosage form: FOR ANIMAL USE ONLY

(spinosad)

Chewable Tablets

For information on dogs, see reverse side.

Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

Description:

Comfortis (spinosad) is available in four sizes of chewable flavored tablets for oral administration to cats and kittens according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dosage of 22.5 mg/lb (50 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions 2-[(6-deoxy-2,3,4 tri-O-methyl-α-L-mannopyranosyl)oxy]-13- [[5 (dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]- 9 ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16btetradecahydro- 14-methyl-1H-as-indaceno[3,2-d] oxacyclododecin-7,15-dione and 2-[(6-deoxy-2,3,4-tri-Omethyl- α-L-mannopyranosyl)oxy] 13-[[5-(dimethylamino) tetrahydro-6-methyl-2H-pyran-2 yl]oxy]-9-ethyl-2,3,3a,5a,5b, 6,9,10,11,12,13,14,16a,16b tetradecahydro-4,14-dimethyl- 1H-as-indaceno[3,2 d]oxacyclododecin-7,15-dione, respectively.

Indications:

Comfortis kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on cats and kittens 14 weeks of age and older and two pounds of body weight or greater.

Dosage and Administration:

Comfortis is given orally once a month, at the minimum dosage of 22.5 mg/lb (50 mg/kg).

Do not use the dosing schedule below when administering Comfortis to dogs, as it can result in an overdosage.

Dosage Schedule:

*Cats over 24 lbs should be administered the appropriate combination of tablets.

Body WeightSpinosad Per Tablet
(mg)
Tablets
Administered
2 to 4 lbs