Generic name:prochlorperazine (oral route) [ proe-klor-PER-a-zeen-MAL-ee-ate ]
Drug classes:Phenothiazine antiemetics, Phenothiazine antipsychotics
Medically reviewed by Drugs.com. Last updated on Apr 19, 2022.
Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared with placebo. Although the causes of death in clinical trials were varied, most deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Prochlorperazine maleate is not approved for the treatment of patients with dementia-related psychosis .
The Compazine brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Commonly used brand name(s)
In the U.S.
- Compazine
Available Dosage Forms:
- Tablet
Therapeutic Class: Antiemetic
Pharmacologic Class: Prochlorperazine
Chemical Class: Prochlorperazine
Uses for Compazine
Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety. It is also used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.
This medicine is available only with your doctor's prescription.
Before using Compazine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the g..
