Generic name:prochlorperazine (rectal route) [ proe-klor-PER-a-zeen ]
Drug classes:Phenothiazine antiemetics, Phenothiazine antipsychotics
Medically reviewed by Drugs.com. Last updated on May 1, 2022.
Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared with placebo. Although the causes of death in the clinical trials were varied, most deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to the patient characteristics. Prochlorperazine is not approved for the treatment of patients with dementia-related psychosis .
The Compazine brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Commonly used brand name(s)
In the U.S.
- Compazine
- Compro
In Canada
- Pms-Prochlorperazine
- Stemetil
Available Dosage Forms:
- Suppository
Therapeutic Class: Antiemetic
Pharmacologic Class: Phenothiazine
Chemical Class: Piperazine (class)
Uses for Compazine
Prochlorperazine suppository is used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.
This medicine is available only with your doctor's prescription.
Before using Compazine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it ..
