Complex HQ Plus
Generic name:hydroquinone
Dosage form: topical emulsion
Drug class:Topical depigmenting agents
Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
On This Page
Rx only
For External Use Only.
Description
Complex HQplus contains: Hydroquinone 40 mg/gm.
Active Ingredient
Hydroquinone, 4%
Clinical Pharmacology:
Topical application of Hydroquinone produces
a reversible depigmentation of the skin by inhibition of the enzymatic
oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (dopa) and
suppression of other melanocyte processes. The selective inhibition
of the enzyme affects melanogenesis in the melanocytes resulting
in cessation of melanin formation and subsequent reduction in
pigmentation. Additional studies indicate Hydroquinone acts on
the essential subcellular metabolic processes of melanocytes with
resultant cytolysis, i.e. nonenzymediated depigmentation.
Exposure to sunlight or ultraviolet light will cause repigmentation
of the bleached areas, which may be prevented by the use of
sunblocking agents.
Indications & Usage:
Complex HQ Plus is indicated for the gradual
lightening of hyperpigmented skin conditions, such as chloasma,
melasma, freckles, senile lentigines, and other unwanted areas of
melanin hyperpigmentation. Sunscreen must be used daily during
Complex HQ Plus treatment.
Contraindications:
Prior history of sensitivity or allergic reaction
to this product or any of its ingredients. The safety of topical
hydroquinone use during pregnancy or in children (12 years and
under) has not been established.
Warnings
A. Caution: Hydroquinone is a skin bleaching agent which may
produce unwanted cosmetic effects if not used as directed. The
physician should be familiar with the contents of this insert before
prescribing or dispensing this medication.
B. Test for skin sensitivity before using Hydroquinone Crea
