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Compro rectal
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Compro (rectal)

Generic name:prochlorperazine (rectal) [ pro-klor-PER-a-zeen ]
Drug classes:Phenothiazine antiemetics, Phenothiazine antipsychotics

Medically reviewed by Drugs.com on Apr 14, 2022. Written by Cerner Multum.

What is rectal Compro?

Compro is used to control severe nausea and vomiting in adults.

Compro may also be used for purposes not listed in this medication guide.

Warnings

You should not use Compro if you have recently used alcohol, sedatives, tranquilizers, or opioid medication.

Compro is not approved for use in older adults with dementia-related psychosis.

Do not give Compro to a child younger than 2 years old or weighing less than 20 pounds.

Before taking this medicine

You should not use Compro if you are allergic to it, or if you have recently used alcohol, sedatives, tranquilizers, or opioid medication.

Do not give this medicine to a child younger than 2 years old or weighing less than 20 pounds. Talk with your doctor before giving this medicine to a child of any age who has been ill with a fever or flu symptoms.

Compro may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

Tell your doctor if you have ever had:

  • heart disease;

  • cancer;

  • bone marrow suppression;

  • an infectious disease such as chickenpox, measles, stomach flu, or an infection of the central nervous system;

  • an enlarged prostate or urination problems;

  • a seizure;

  • glaucoma; or

  • pheochromocytoma (tumor of the adrenal gland).

Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are using Compro.

Tell your doctor if you are pregnant. Using Compro in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How should I use rectal Compro?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take a rectal suppository by mouth. It is for use only in your rectum.

Wash your hands before and after inserting the suppository.

Remove the wrapper before inserting the suppository. Avoid handling the suppository too long or it will melt. Li...