Medically reviewed by Drugs.com. Last updated on Apr 27, 2022.
Estrogen treatment alone increases the risk of endometrial cancer in a woman with a uterus. Adding a progestin to estrogen therapy may reduce the risk of endometrial hyperplasia, a precursor to endometrial cancer. However, addition of a progestin to estrogen therapy may increase the risk of invasive breast cancer. Undertake adequate diagnostic measures, including directed or random endometrial sampling if indicated, to rule out malignancy in postmenopausal women with abnormal vaginal bleeding. Estrogen treatment alone increased risks of stroke and deep vein thrombosis (DVT), while estrogen plus progestin increased risks of stroke, DVT, myocardial infarction, and pulmonary emboli in postmenopausal women (50 to 79 years of age). Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported. Prescribe estrogen with or without progestins at the lowest effective dose and for the shortest duration .
Commonly used brand name(s)
In the U.S.
- Cenestin
Pharmacologic Class: Estrogen
Uses for conjugated estrogens synthetic a
Conjugated estrogens synthetic A is used to treat moderate to severe hot flashes and other symptoms of menopause or low amounts of estrogen. It is also used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by menopause.
Conjugated estrogens synthetic a is available only with your doctor's prescription.
Before using conjugated estrogens synthetic a
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For conjugated estrogens synthetic a, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to conjugated estrogens synthetic a or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or a..
