Corzall

Generic name:carbetapentane citrate, pseudoephedrine hydrochloride
Dosage form: liquid
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Aug 23, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Corzall Liquid

Rx Only
Antitussive / Decongestant

DESCRIPTION

Each teaspoonful (5 mL) for oral administration contains:
Carbetapentane Citrate..... 20 mg
Pseudoephedrine Hydrochloride..... 30 mg

Inactive ingredients: Citric Acid, Glycerin, Grape Flavor, Propylene Glycol, Purified Water, Sodium Citrate,
Sodium Saccharin, Sorbitol.

Carbetapentane Citrate (1-Phenylcyclopentanecarboxylic acid, 2-(2-diethylaminoethoxy) ethyl ester citrate) is a white
crystalline powder. It is freely soluble in water and chloroform. Its structure is as follows:

Pseudoephedrine Hydrochloride (Benzenemethanol, α-[1-(methylamino)ethyl]-, [S-(R*,R*)-, hydrochloride) is the
hydrochloride of pseudoephedrine, a naturally occurring dextrorotatory stereoisomer of ephedrine. Its structure
is as follows:

Corzall - Clinical Pharmacology

Antitussive and decongestant actions.

Carbetapentane citrate is a centrally acting non-narcotic antitussive. Carbetapentane citrate has atropine-like and local
anesthetic actions, as well as temporarily controls and suppresses the cough reflex by selective depression of the
medullary cough center. It has no significant analgesic or sedative properties, does not depress respiration or predispose
to addiction with usual doses.

Pseudoephedrine hydrochloride is an oral sympathomimetic amine that acts as a decongestant to respiratory tract
mucous membranes. While its vasoconstrictor action is similar