Crantex
Generic name:hrine hydrochloride and guaifenesin
Dosage form: oral liquid
Drug class:Upper respiratory combinations
Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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ACTIVE INGREDIENTS: Each 5 mL (teaspoonful) contains:
Phenylephrine Hydrochloride ..... 7.5 mg
Guaifenesin ..... 100 mg
INACTIVE INGREDIENTS: Citric Acid, Orange Flavoring, Sorbitol Solution, Propylene Glycol, Purified Water, Saccharin Sodium, Sodium Benzoate, and Sodium Chloride.
Phenylephrine hydrochloride
Benzenemethanol,3-hydroxy-α-[(methylamino) methyl]-hydrochloride (R)-., is an adrenergic, which occurs as white or practically white, odorless crystals having a bitter taste. It is freely soluble in water and alcohol.
Guaifenesin
1,2-Propanediol, 3-(2-methoxyphenoxy)-, (±)-., is a white to slightly gray, crystalline powder, having a bitter taste. It may have a slight characteristic odor. It is soluble in water, alcohol, chloroform, glycerin, and propylene glycol.
Crantex - Clinical Pharmacology
Phenylephrine HCI is a sympathomimetic which acts predominantly on alpha receptors and has little action on beta receptors, therefore it functions as an oral nasal decongestant with minimal CNS stimulation. Guaifenesin has an expectorant action which increases the output of respiratory tract fluid by reducing adhesiveness and surface tension. Sinus and bronchial drainage is improved and dry, non-productive coughs become more productive and less frequent.
Indications and Usage for Crantex
For temporary relief of symptoms associated with the common cold, influenza, and bronchitis.
Contraindications
Crantex Liquid® is contraindicated in infants and newborns, and in patients with a known hypersensitivity to any of the components. It is also contraindicated in patients with severe hypertension, severe coronary artery disease, hyperthyroidism, and in patients on MAO inhibitor thera..
