C-Topical Solution

Generic name:cocaine hydrochloride
Dosage form: topical solution
Drug class:Topical anesthetics

Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

C-Topical Solution Description

Each mL contains:

Cocaine hydrochloride 40 mg or 100 mg As aqueous solution.

The topical solution contains the following inactive ingredients: citric acid, sodium benzoate, D&C Yellow No. 10, FD&C Green No. 3, and purified water.

NOTE (for Glass Bottle): External surface of unopened bottle may be sterilized by ethylene oxide only. Do not steam autoclave.

Cocaine hydrochloride USP is a crystalline, granular, or powder substance having a saline, slightly bitter taste that numbs tongue and lips. Cocaine hydrochloride is a local anesthetic.

C-Topical Solution - Clinical Pharmacology

Cocaine blocks the initiation or conduction of the nerve impulse following local application, thereby effecting local anesthetic action.

Cocaine is absorbed from all sites of application, including mucous membranes and the gastrointestinal mucosa. Cocaine is degraded by plasma esterses, with the half-life in the plasma being approximately one hour.

Indications and Usage for C-Topical Solution

C-Topical is indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.

Contraindications

Cocaine hydrochloride is contraindicated in patients with a known history of hypersensitivity to the drug or to the components of the topical solution.