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Cymbalta
  • Treatments
  • Fibromyalgia

Cymbalta

Generic name:duloxetinedu-LOX-e-teen ]
Drug class:Serotonin-norepinephrine reuptake inhibitors

Medically reviewed by Kaci Durbin, MD. Last updated on Dec 2, 2021.

What is Cymbalta?

Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression.

Cymbalta is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old.

Cymbalta is also used in adults to treat nerve pain caused by diabetes (diabetic neuropathy), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).

Cymbalta is also used to treat fibromyalgia (a chronic pain disorder) in adults and children at least 13 years old.

Warnings

Do not take Cymbalta within 5 days before or 14 days after you have used a MAO inhibitor, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine, or methylene blue injection.

Cymbalta should not be used if you have narrow angle glaucoma.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

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