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Cyproheptadine
  • Treatments
  • Migraine

Cyproheptadine

Generic name: cyproheptadine [ SIP-roe-HEP-ta-deen ]
Brand name: Periactin
Dosage forms: oral syrup (2 mg/5 mL); oral tablet (4 mg)
Drug class:Antihistamines

Medically reviewed by Drugs.com on Sep 20, 2021. Written by Cerner Multum.

What is cyproheptadine?

Cyproheptadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Cyproheptadine is used to treat sneezing, runny nose, itching, red or watery eyes, and other symptoms of seasonal allergies (hay fever). Cyproheptadine is also used to treat other conditions such as eczema or skin reactions to insect bites.

Cyproheptadine is sometimes used to treat certain types of headaches, including migraines.

Cyproheptadine may also be used for purposes not listed in this medication guide.

Warnings

You should not use cyproheptadine if you have narrow-angle glaucoma, a stomach ulcer or obstruction, an enlarged prostate, urination problems, or if you are having an asthma attack. You also should not use cyproheptadine if you are breast-feeding a baby, if you are elderly, or if you have a debilitating disease.

Do not use cyproheptadine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid,