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Cyramza
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Cyramza

Generic name:ramucirumabRA-mue-SIR-ue-mab ]
Drug class:VEGF/VEGFR inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on Dec 27, 2021.

What is Cyramza?

Cyramza is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Cyramza is used to treat stomach cancer, colorectal cancer, or non-small cell lung cancer that has spread to other parts of the body, and hepatocellular carcinoma. Ramucirumab may be given alone or in combination with other cancer medicines.

Cyramza is usually given after other cancer medicines have been tried without success.

Warnings

Cyramza can increase your risk of serious bleeding. Stop using this medicine and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.

Before taking this medicine

You should not use Cyramza if you are allergic to ramucirumab, or if you have ever had:

  • uncontrolled high blood pressure.

To make sure Cyramza is safe for you, tell your doctor if you have:

  • high blood pressure;

  • a thyroid disorder; or

  • an unhealed incision from recent surgery.

This medicine can harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. Ramucirumab may affect fertility (your ability to have children).

Use birth control to prevent pregnancy while you are receiving Cyramza, and for at least 3 months after your treatment ends.

You should not breastfeed while using ramucirumab.

How is Cyramza given?

Cyramza is given as an infusion into a vein through an IV. A healthcare provider will give you this infusion.

You may be given medication to prevent certain side effects while you are receiving this medicine.

Cyramza is sometimes given once every 2 weeks. It may also be given in a 21-day treatment cycle and you may only need to use the medicine during the first day of each cycle. Follow your doctor's dosing instructions very carefully.

While using Cyramza, you may need frequent blood or urine tests. Your blood pressure will need to be checked often.

If you need surgery, tell the surgeon ahead of time that you are using Cyramza. You may need to stop using the medicine for a short time.

What happens if I miss a dose?

Call your doctor for instructions if you m...