Cytarabine and daunorubicin (liposomal)
Generic name: cytarabine and daunorubicin (liposomal) [ sye-TAR-a-been-and-DAW-noe-ROO-bi-sin ]
Brand name: Vyxeos
Dosage form: intravenous powder for injection (100 mg-44 mg)
Drug class:Antineoplastic combinations
What is cytarabine and daunorubicin liposomal?
Cytarabine and daunorubicin liposomal is a combination medicine used to treat acute myeloid leukemia that is newly diagnosed in adults and children at least 1 year old.
Cytarabine and daunorubicin liposomal may also be used for purposes not listed in this medication guide.
Warnings
cytarabine and daunorubicin can make it easier for you to bleed. Contact your doctor or seek emergency medical attention if you have easy bruising, unusual bleeding, or any bleeding that will not stop. You may also have bleeding on the inside of your body, such as in your stomach or intestines, or in your brain.
Call your doctor at once if you have: signs of bleeding in your digestive tract--feeling very weak or dizzy, severe stomach pain, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds; or signs of bleeding in the brain--sudden numbness or weakness (especially on one side of the body), sudden severe headache, or problems with vision or balance.
Before taking this medicine
You should not be treated with this medicine if you are allergic to cytarabine or daunorubicin.
Tell your doctor if you have ever had:
heart disease;
liver or kidney disease;
radiation treatment of your chest area; or
Wilson's disease (a rare genetic disorder).
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using this medicine should use effective birth control to prevent pregnancy. Cytarabine and daunorubicin liposomal can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 6 months after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using this medicine.
It may be harder for you to get a woman pregnant while you are using this medicine. You should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
You should not breastfeed while using this medicine and for at least 2 weeks after your last dose.
How is cytarabine and daunorubicin liposomal given?
The liposomal combination of cytarab...
