Darunavir

Generic name: darunavir [ da-ROON-a-veer ]
Brand name: Prezista
Dosage forms: oral suspension (100 mg/mL); oral tablet (150 mg; 600 mg; 75 mg; 800 mg)
Drug class:Protease inhibitors

Medically reviewed by Drugs.com on Apr 28, 2022. Written by Cerner Multum.

What is darunavir?

Darunavir is an antiviral medicine that is used to treat HIV (human immunodeficiency virus). HIV can cause acquired immunodeficiency syndrome (AIDS). Darunavir is not a cure for HIV or AIDS.

Darunavir must be given in combination with ritonavir and other antiviral medications and should not be used alone.

Darunavir may also be used for purposes not listed in this medication guide.

Warnings

Stop taking darunavir and call your doctor right away if you have a severe skin reaction: fever, burning or redness in your eyes, mouth sores, or a skin rash that spreads and causes blistering and peeling.

Tell your doctor about all your other medicines. Some drugs should not be used with darunavir.

Darunavir can cause serious liver problems. Call your doctor if you have upper stomach pain, loss of appetite, tiredness, dark urine, clay-colored stools, or yellowing of your skin or eyes.

Before taking this medicine

You should not take darunavir if you have severe liver disease.

Some drugs should not be used with darunavir. Your treatment plan may change if you also use:

• alfuzosin;

• cisapride;

• colchicine (in people with liver or kidney disease);

• dronedarone;

• elbasvir and grazoprevir;

• lurasidone;

• naloxegol;

• pimozide;

• rifampin;

• sildenafil (Revatio, for pulmonary arterial hypertension);

• St. John's wort;

• triazolam or oral midazolam;

• heart medicine--ivabradine, ranolazine;

• cholesterol medication--lomitapide,